Genefinder

Record added by Jurg Ott (the original Rockefeller list)

1.1.9 (June 2004)

GeneFinder uses GEE method to estimate the location of the susceptibility gene based on the allele-sharing of affected sib pairs for multiple markers. GENEFINDER can further the analysis of GENEHUNTER by providing a more accurate gene location estimation and the corresponding confidence interval.

• Wei-Min Chen (email: wechen@jhsph.edu)
• Kung-Yee Liang (email: kyliang@jhpsh.edu)
• Yen-Feng Chiu

http://www.biostat.jhsph.edu/~wmchen/gf.html

C++

MS-Windows, MS-DOS, UNIX(Solaris)

gf

• Liang KY, Zeger SL (1986), “Longitudinal data analysis using generalized linear models”, Biometrika, 73: 13-22.
• Liang KY, Chiu YF, Beaty TH (2001), “A robust identity by descent procedure using affected sib pairs: a multipoint approach for complex diseases”, Human Heredity, 51:64-78.
• Liang KY, Chiu YF, Beaty TH, Wjst Matthias (2001), “A multipoint analysis using affected sib pairs: incorporation of linkage evidence from unlinked regions”, Genetic Epidemiology, 21:105-122.
• Liang KY, Huang CY, Beaty TH (2000) A unified sampling approach for multipoint analysis of qualitative and quantitative traits in sib pairs. American Journal Human Genetics, 66(5):1631-1641
• Glidden DV, Liang KY, Chiu YF, Pulver AE (2003), “Multipoint affected sibpair linkage methods for localizing susceptibility genes of complex diseases”, Genetic Epidemiology, 24:107-117