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Hap Sample

HAP-SAMPLE

Record added by Jurg Ott (the original Rockefeller list)

Description

HAP-SAMPLE is a web application for simulating SNP genotypes for case-control and affected-child trio studies by resampling from Phase I/II HapMap SNP data. The user provides a list of SNPs to be “genotyped,” along with a disease model file that describes causal SNPs and their effect sizes. The simulation tool is appropriate for candidate regions or whole-genome scans.

URL

http://www.hapsample.org/

OS

web-based

Reference

Wright, Huang, Guan, Gamiel, Jeffreis, Barry, Pardo-Manuel, Sullivan, Wilhelmsen, Zou (2007), “Simulating association studies: a data-based resampling method for candidate regions or whole genome scans”, preprint.