Lamp

Record added by Jurg Ott (the original Rockefeller list)

Linkage and Association Modeling in Pedigrees

0.0.9

LAMP carries out parametric association analysis in samples of unrelated individuals, trios or large families. In addition to a test-statistic, a genetic model is estimated for each SNP. The approach is based on retrospective likelihood and can be used to analyze selected samples.

• Goncalo Abecasis (email: goncalo@umich.edu)
• Mingyao Li

http://www.sph.umich.edu/csg/abecasis/LAMP/download/

C++

UNIX, LINUX, MS-Windows, MacOS

lamp

• Li, Boehnke, Abecasis (2006), “Efficient study designs for test of genetic association using sibship data and unrelated cases and controls”, American Journal of Human Genetics, 78(5):778-792
• Li, Boehnke, Abecasis (2005), “Joint Modeling of Linkage and Association: Identifying SNPs Responsible for a Linkage Signal”, American Journal of Human Genetics, 76(6):934-949