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Margarita

MARGARITA

Record added by Jurg Ott (the original Rockefeller list)

Description

Margarita infers genealogies from population genotype data and uses these to map disease loci. These genealogies take the form of the Ancestral Recombination Graph (ARG). The ARG defines a genealogical tree for each locus, and as one moves along the chromosome the topologies of consecutive trees shift according to the impact of historical recombination events.

Author

Richard Durbin (Wellcome Trust Sanger Institute)

URL

http://www.sanger.ac.uk/resources/software/margarita/

Language

Java