ROM Prev

Record added by Jurg Ott (the original Rockefeller list)

Regression of Offspring on Mid-Parent (REVised)

0.2.1beta

a software tool for testing for association between polymorphisms and quantitative traits, as well as estimating trait heritability and locus-specific heritability using family data.

• Marie-Helene Roy-Gagnon
• Alexander F. Wilson (afw@mail.nih.gov)

• http://research.nhgri.nih.gov/ROMPrev/
• ftp://ftp.nhgri.nih.gov/pub/software/ROMPrev/

R

any with R installation

• Roy-Gagnon, Mathias, Fallin, Jee, Broman, Wilson (2008), “An extension of the Regression of Offspring on Mid-Parent to test for association and estimate locus-specific heritability: The revised ROMP method”, Annals of Human Genetics, 72:115-125.
• Roy-Gagnon (2004), “Theoretical and applied investigations of a Regression of Offspring on Mid-Parent approach: Familial idiopathic scoliosis”, Ph.D. dissertaion. Johns Hopkins University.
• Pugh, Papanicolaou, Justice, Roy-Gagnon, Sorant, Kingman, Wilson (2001), “Comparison of variance components, ANOVA and regression of offspring on midparent (ROMP) methods for SNP markers”, Genetic Epidemiology, 21(Suppl 1):S794-S799.