Spreg

Record added by Jurg Ott (the original Rockefeller list)

Secondary Phenotype REGression analysis

2.0

SPREG is a computer program for performing regression analysis of secondary phenotype data in case-control association studies. Secondary phenotypes are quantitative or qualitative traits other than the case-control status. Because the case-control sample is not a random sample of the general population, standard statistical analysis of secondary phenotype data can yield very misleading results. SPREG implements valid and efficient statistical methods.

• Danyu Lin
• Donglin Zeng (Univ North Carolina)

http://www.bios.unc.edu/~lin/software/SPREG/

C

Lin, Zeng (2009), “Proper analysis of secondary phenotype data in case-control association studies”, Genetic Epidemiology, 33:256-265.